Just a list of Knowledge Skill ideas that I found.  Add to the list as you see fit.

• 20th Century Comic Books
• Alcohol
• Anthropology
• Application Design
• Archaeology
• Area Knowledge
• Arms Dealers
• Art
• Artificial Intelligence
• Astrology
• (Chinese)
• (Mayan)
• (Native American)
• (Vedic)
• (Western)
• Atlantis Research
• Automated Factory Familiarity
• BTL Dealers
• BTL Production
• Biology
• Biotechnology
• Black IC Design
• Body Armor Fabrication
• Botany
• Bushido Philosophy
• Cellular Network Familiarity
• Chat Room Familiarity
• Chat Rooms
• Cheap Synthahol Guzzling
• Chemistry
• (Pharmeceuticals)
• Chokepoint Familiarity
• Chop Shops
• Civil Engineering
• (Commercial Construction)
• (Excavation)
• (Home Construction)
• (Industrial Construction)
• (Tunneling)
• Combat Biking
• Communications Satellite Familiarity
• Computer Background
• Conspiracy Theories
• Cooking
• Corporate Finances
• Corporate Hosts
• Corporate Politics
• Corporate Program Designers
• Corporate Rumors
• Criminal Organizations
• Current Events
• Cyberdecks
• Cybertechnology
• Cyberterminal Code Design
• Cyberterminal Design
• Data Archive Familiarity
• Data Brokerage
• Data Havens
• Data Tracing
• Databases
• Decker Tricks
• Deckmeisters
• Defensive Utility Design
• Demolitions Background
• Desert Wars
• Dowsing
• (Bobber)
• (Compass)
• (L-Rod)
• (Pendulum)
• (Y-Rod)
• Dragons
• Drugs
• Ecology
• (Sewers)
• Economics
• Electronics Background
• Elven Society
• Elven Wines
• Engineering
• Esoteric Trivia
• Fences
• Flatvid Movies
• Forensics
• Frame Core Design
• Fringe Cults
• Gambling Card Games
• Game Host Familiarity
• Gang Identification
• (Go-Gangs)
• Gang Turf
• Gear Value
• Geology
• Gray IC Design
• Gunsmithing
• Hardcore Punk Bands
• History
• Humanis Policlub
• IC Construct Design
• IC Profiles
• Iconography
• Jackpoint Locations
• Japanese Culture
• Japanese Society
• LTG Familiarity
• Legendary Deckers
• Legendary Martial Artists
• Literature
• Local Landmarks
• Local Politics
• Local Rumor Mill
• Lone Star Tactics
• Mafia Finances
• Mafia Politics
• Mafia-Controlled Establishments
• Magic Background
• Magical Goods Value
• Magical Groups
• Magical Threats
• Matrix Bank Familiarity
• Matrix Gangs
• Matrix Programs
• Matrix Security Procedures
• Matrix Topography
• Mechanical Traps
• Medicine
• (Pathology)
• (Toxicology)
• (Traumatology)
• Meditation
• Megacorporate Policies
• Megacorporate Politics
• Megacorporate Research
• Megacorporate Security
• Mercenary Groups
• Mercenary Hot Spots
• Metahumanity
• Metallurgy
• Metalworking
• Microchips
• Military Winged Aircraft
• Miltech Manufacturers
• Modern Art
• Modern Jazz
• Music
• NAN Border Patrol Tactics
• Named Spirits
• Offensive Utility Design
• Opera
• Operational Utility Design
• Parabotany
• Paranormal Animals
• (Urban)
• Parapsychology
• Parazoology
• Philosophy
• Physics
• (Ballistics)
• Pirate Trid Broadcasters
• Poetry
• Police Procedures
• Politics
• Professional Bodyguarding
• Programming Suite Design
• Prostitution Rings
• Psychology
• RTG Familiarity
• Redmond Barrens
• Roleplaying Games of the Late 20th Century
• Rumor Mill
• SWAT Team Tactics
• Safehouse Locations
• Satellite Networks
• Sci-Fi Simchips
• Scrounging
• Sculpture
• Seattle Corporate Hosts
• Seattle High Society
• Seattle Junkyards
• Seattle LTG
• Seattle Ork Underground
• Security Companies
• Security Design
• (Closed Circuit Simsense)
• (Corporate)
• (Magical)
• (Matrix)
• (Military)
• (Physical)
• (Private Home)
• Security Network Familiarity
• Security Procedures
• (Government)
• (Military)
• Seedy Ork Bars
• Shadowrunner Haunts
• Shadowrunner Teams
• Sim Starlets
• Small Unit Tactics
• (Vehicle Tactics)
• Smuggler Havens
• Smuggler Routes
• Sociology
• Special Utility Design
• Spell Design
• Street Rumors
• Talismongering
• (Gathering)
• Tir Tairngire Politics
• Toxic Hazards
• Trace IC Design
• Tracking
• Troll Thrash Metal Bands
• Triad Politics
• Tribal Lore
• Tribal Politics
• Underworld Finance
• Underworld Politics
• Urban Brawl
• Virtual Meeting Spots
• Weapon Acquisition
• Weightlifting
• White IC Design
• Woodworking
• Worm Design
• Yakuza Territory
• Zoology
• (Wilderness)